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Emergency Lung Transplantation after COVID-19: Immunopathological Insights on Two Affected Patients.

Cells - 10 Mar 2021

Croci Giorgio A, Vaira Valentina, Trabattoni Daria, Biasin Mara, Valenti Luca, Baselli Guido, Barberis Massimo, Guerini Rocco Elena, Gregato Giuliana, Scandroglio Mara, Fominskiy Evgeny, Palleschi Alessandro, Rosso Lorenzo, Nosotti Mario, Clerici Mario, Ferrero Stefano

Abstract excerpt

We herein characterize the immunopathological features of two Italian COVID-19 patients who underwent bilateral lung transplantation (bLTx). Removed lungs underwent histopathological evaluation. Gene expression profiling (GEP) for immune-related signatures was performed on lung specimens and SARS-CoV-2-stimulated peripheral blood mononuclear cells (PBMCs). Cytokine levels were measured on lungs, bronchoalveolar...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33801959
DOI: 10.3390/cells10030611
PMCID: PMC7999589

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