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Oropharyngeal Squamous Cell Carcinoma Morphology and Subtypes by Human Papillomavirus Type and by 16 Lineages and Sublineages.

Head and neck pathology - 1 Dec 2021

Lewis James S, Mirabello Lisa, Liu Ping, Wang Xiaowei, Dupont William D, Plummer W Dale, Pinheiro Maisa, Yeager Meredith, Boland Joseph F, Cullen Michael, Steinberg Mia, Bass Sara, Mehrad Mitra, O'Boyle Connor, Lin Maoxuan, Faden Daniel L, Lang-Kuhs Krystle A

Abstract excerpt

Oropharyngeal squamous cell carcinoma (SCC) is increasing in incidence and, in Western countries, strongly associated with transcriptionally-active high-risk human papillomavirus (HPV). Within HPV-positive tumors, there is wide morphologic diversity with numerous histologic subtypes of SCC. There are also variable degrees of keratinization, anaplasia, stromal fibrosis, and maturing squamous differentiation....

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to High-Throughput Nucleotide Sequencing

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Identifiers

PMID: 33797697
DOI: 10.1007/s12105-021-01318-4
PMCID: PMC8633182

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