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Article

Whole genome sequencing in cats, identifies new models for blindness in AIPL1 and somite segmentation in HES7.

BMC genomics - 31 Mar 2016

Lyons Leslie A, Creighton Erica K, Alhaddad Hasan, Beale Holly C, Grahn Robert A, Rah HyungChul, Maggs David J, Helps Christopher R, Gandolfi Barbara

Abstract excerpt

BACKGROUND: The reduced cost and improved efficiency of whole genome sequencing (WGS) is drastically improving the development of cats as biomedical models. Persian cats are models for Leber's congenital amaurosis (LCA), the most severe and earliest onset form of visual impairment in humans. Cats with innocuous breed-defining traits, such as a bobbed tail, can also be models for somite segmentation and vertebral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27030474
DOI: 10.1186/s12864-016-2595-4
PMCID: PMC4815086

Genes

AIPL1
HES7

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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