Article
A new domestic cat genome assembly based on long sequence reads empowers feline genomic medicine and identifies a novel gene for dwarfism.
PLoS genetics - 1 Oct 2020
Buckley Reuben M, Davis Brian W, Brashear Wesley A, Farias Fabiana H G, Kuroki Kei, Graves Tina, Hillier LaDeana W, Kremitzki Milinn, Li Gang, Middleton Rondo P, Minx Patrick, Tomlinson Chad, Lyons Leslie A, Murphy William J, Warren Wesley C
Abstract excerpt
The domestic cat (Felis catus) numbers over 94 million in the USA alone, occupies households as a companion animal, and, like humans, suffers from cancer and common and rare diseases. However, genome-wide sequence variant information is limited for this species. To empower trait analyses, a new cat genome reference assembly was developed from PacBio long sequence reads that significantly improve sequence...
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