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Dissecting the molecular diversity and commonality of bovine and human treponemes identifies key survival and adhesion mechanisms

29 Mar 2021

Abstract excerpt

Here, we report the first complete genomes of three cultivable treponeme species from bovine digital dermatitis (DD) skin lesions, two comparative human treponemes, considered indistinguishable from bovine DD species, and a bovine gastrointestinal (GI) treponeme isolate. Key genomic differences between bovine and human treponemes implicate microbial mechanisms that enhance knowledge of how DD, a severe disease of...

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PMID: 33780514
DOI: 10.1371/journal.ppat.1009464

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