Article
A novel approach to probe host-pathogen interactions of bovine digital dermatitis, a model of a complex polymicrobial infection.
BMC genomics - 1 Dec 2016
Marcatili Paolo, Nielsen Martin W, Sicheritz-Pontén Thomas, Jensen Tim K, Schafer-Nielsen Claus, Boye Mette, Nielsen Morten, Klitgaard Kirstine
Abstract excerpt
BACKGROUND: Polymicrobial infections represent a great challenge for the clarification of disease etiology and the development of comprehensive diagnostic or therapeutic tools, particularly for fastidious and difficult-to-cultivate bacteria. Using bovine digital dermatitis (DD) as a disease model, we introduce a novel strategy to study the pathogenesis of complex infections. RESULTS: The strategy combines...
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