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Article

Non-responder phenotype reveals apparent microbiome-wide antibiotic tolerance in the murine gut.

Communications biology - 9 Mar 2021

Diener Christian, Hoge Anna C H, Kearney Sean M, Kusebauch Ulrike, Patwardhan Sushmita, Moritz Robert L, Erdman Susan E, Gibbons Sean M

Abstract excerpt

Broad spectrum antibiotics cause both transient and lasting damage to the ecology of the gut microbiome. Antibiotic-induced loss of gut bacterial diversity has been linked to susceptibility to enteric infections. Prior work on subtherapeutic antibiotic treatment in humans and non-human animals has suggested that entire gut communities may exhibit tolerance phenotypes. In this study, we validate the existence of...

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Identifiers

PMID: 33750910
DOI: 10.1038/s42003-021-01841-8
PMCID: PMC7943787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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