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Article

ERBB1/2/3 Expression, Prognosis, and Immune Infiltration in Cutaneous Melanoma

1 Mar 2021

Abstract excerpt

Background The four ERBB tyrosine kinase family members [ERBB1 (epidermal growth factor receptor, EGFR), ERBB2 (HER2), ERBB3 (HER3), and ERBB4 (HER4)] (ERBB receptor family) have been shown, according to previous studies, to be related to the cutaneous melanoma. ERBB3 is the only member of the ERBBs that lacks tyrosine kinase activity and thus needs to dimer with other tyrosine kinases receptors to trigger the...

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Identifiers

PMID: 33732282
DOI: 10.3389/fgene.2021.602160

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