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Article

YAP promotes autophagy and progression of gliomas via upregulating HMGB1

16 Mar 2021

Abstract excerpt

BACKGROUND: Due to the hypoxia and nutrient deficiency microenvironment, glioblastoma (GBM) exhibits high autophagy activity and autophagy plays an important role in the progression of GBM. However, the molecular mechanism of autophagy in GBM progression remains unclear. The aim of this study is to delve out the role and mechanism of yes-associated protein (YAP) in GBM autophagy and progression. METHODS: The...

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Share to Autophagy in Disease and Therapy
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PMID: 33726796
DOI: 10.1186/s13046-021-01897-8

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