Clinical impact of probiotics on the efficacy of anti-PD-1 monotherapy in patients with nonsmall cell lung cancer: A multicenter retrospective survival analysis study with inverse probability of treatment weighting.

doi:10.1002/ijc.33557

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Article

Clinical impact of probiotics on the efficacy of anti-PD-1 monotherapy in patients with nonsmall cell lung cancer: A multicenter retrospective survival analysis study with inverse probability of treatment weighting.

International journal of cancer - 15 Jul 2021

Takada Kazuki, Shimokawa Mototsugu, Takamori Shinkichi, Shimamatsu Shinichiro, Hirai Fumihiko, Tagawa Tetsuzo, Okamoto Tatsuro, Hamatake Motoharu, Tsuchiya-Kawano Yuko, Otsubo Kohei, Inoue Koji, Yoneshima Yasuto, Tanaka Kentaro, Okamoto Isamu, Nakanishi Yoichi, Mori Masaki

Abstract excerpt

The gastrointestinal microbiota was reported as an important factor for the response to cancer immunotherapy. Probiotics associated with gastrointestinal dysbiosis and bacterial richness may affect the efficacy of cancer immunotherapy drugs. However, the clinical impact of probiotics on the efficacy of cancer immunotherapy in patients with nonsmall cell lung cancer (NSCLC) is poorly understood. The outcomes of...

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PMID: 33720422
DOI: 10.1002/ijc.33557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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