Article
CFTR gene variants as a reason for impaired spermatogenesis: a pilot study and a Meta-analysis of published data.
Human fertility (Cambridge, England) - 1 Oct 2022
Levkova Mariya, Chervenkov Trifon, Hachmeriyan Mari, Angelova Lyudmila
Abstract excerpt
There is increasing data that IVS8-5T variand and TG repeats could lead to impaired spermatogenesis. To investigate this we performed Sanger sequencing on 50 Bulgarian men with a sperm count below 5 × 106/mL and 20 normal fertile men. Frequencies of the results were compared among the two groups. A meta-analysis was perfomed by using the data for 6,423 patients and 5,834 control subjects, tested for the IVS8-5T...
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