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Article

Factor VIII levels and bleeding according to factor 8 (F8) mutation in pregnant carriers of haemophilia A: a multicentre retrospective cohort study.

British journal of haematology - 1 Apr 2021

Collins Annie E I, Curry Nicola, Raza-Burton Sayma, Bignell Patricia, Davies Claire, Joffe Michael, Shapiro Susan, Desborough Michael J R

Abstract excerpt

This retrospective cohort study investigated the association between factor 8 (F8) genotype severity and factor VIII (FVIII) levels during pregnancy for 52 women (64 pregnancies) who were heterozygous carriers of mild, moderate or severe haemophilia A. There were no significant differences in FVIII levels for carriers of mild, moderate or severe haemophilia A at baseline [mean (SD) level: mild, 0·78 (0·22);...

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Identifiers

PMID: 33715149
DOI: 10.1111/bjh.17254

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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