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Article

The transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation

4 Mar 2021

Abstract excerpt

was required for adaptive NK cell responses in a murine cytomegalovirus model, supporting expansion of these cells. Together, we define the TF regulatory circuitry of human NK cells and uncover a critical role for Bcl11b in promoting NK cell differentiation and function.

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Identifiers

PMID: 33712472
DOI: 10.1126/sciimmunol.abc9801

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