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Article

Familial hemiplegic migraine type 2 due to a novel missense mutation in ATP1A2.

The journal of headache and pain - 12 Mar 2021

Antonaci Fabio, Ravaglia Sabrina, Grieco Gaetano S, Gagliardi Stella, Cereda Cristina, Costa Alfredo

Abstract excerpt

BACKGROUND: The mechanisms of genotype-phenotype interaction in Familiar Hemiplegic migraine type 2 (FHM2) are still far from clear. Different ATP1A2 mutations have been described, with a spectrum of phenotypes ranging from mild to severe. No genotype-phenotype correlations have been attempted. CASE PRESENTATION: We describe an Italian family with FHM and a missense ATP1A2 variant (L425H) not previously...

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Identifiers

PMID: 33711927
DOI: 10.1186/s10194-021-01221-x
PMCID: PMC7953819

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