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Article

A genomic variant of ALPK2 is associated with increased liver fibrosis risk in HIV/HCV coinfected women.

PloS one - 1 Jan 2021

McIntosh Alec T, Wei Renhuizi, Ahn Jaeil, Aouizerat Brad E, Kassaye Seble G, Augenbraun Michael H, Price Jennifer C, French Audrey L, Gange Stephen J, Anastos Kathryn M, Goldman Radoslav

Abstract excerpt

HIV coinfection is associated with more rapid liver fibrosis progression in hepatitis C (HCV) infection. Recently, much work has been done to improve outcomes of liver disease and to identify targets for pharmacological intervention in coinfected patients. In this study, we analyzed clinical data of 1,858 participants from the Women's Interagency HIV Study (WIHS) to characterize risk factors associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33705408
DOI: 10.1371/journal.pone.0247277
PMCID: PMC7951908

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