Article
In silico analysis of selenoprotein N (Gallus gallus): absence of EF-hand motif and the role of CUGS-helix domain in antioxidant protection.
Metallomics : integrated biometal science - 8 Mar 2021
Zhu Shi-Yong, Liu Li-Li, Huang Yue-Qiang, Li Xiao-Wei, Talukder Milton, Dai Xue-Yan, Li Yan-Hua, Li Jin-Long
Abstract excerpt
Selenoprotein N (SEPN1) is critical to the normal muscular physiology. Mutation of SEPN1 can raise congenital muscular disorder in human. It is also central to maturation and structure of skeletal muscle in chicken. However, human SEPN1 contained an EF-hand motif, which was not found in chicken. And the biochemical and molecular characterization of chicken SEPN1 remains unclear. Hence, protein domains,...
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