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Article

Oxidative stress in SEPN1-related myopathy: from pathophysiology to treatment.

Annals of neurology - 1 Jun 2009

Arbogast Sandrine, Beuvin Maud, Fraysse Bodvaël, Zhou Haïyan, Muntoni Francesco, Ferreiro Ana

Abstract excerpt

OBJECTIVE: Mutations of the selenoprotein N gene (SEPN1) cause SEPN1-related myopathy (SEPN1-RM), a novel early-onset muscle disorder formerly divided into four different nosological categories. Selenoprotein N (SelN) is the only selenoprotein involved in a genetic disease; its function being unknown, no treatment is available for this potentially lethal disorder. Our objective was to clarify the role of SelN and...

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Source

Identifiers

PMID: 19557870
DOI: 10.1002/ana.21644

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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