Male hypogonadism as a candidate of deficiency of postnatal testicular growth or differentiating factor(s): a new autosomal recessive mutation in the rat.

doi:10.1093/oxfordjournals.jhered.a110447

Article

Male hypogonadism as a candidate of deficiency of postnatal testicular growth or differentiating factor(s): a new autosomal recessive mutation in the rat.

The Journal of heredity - 1 Jan 2000

Suzuki K, Hakamata Y, Hamada A, Kikukawa K, Wada M Y, Imamichi T

Abstract excerpt

A new rat mutant showing severe male hypogonadism (hgn for the gene symbol) was found and isolated from the hereditary hydronephrosis rat strain originating from the Wistar-Imamichi rat. The affected rats have very tiny testes that weigh 26 mg in the adult, and contain small numbers of seminiferous tubules with degenerated Sertoli cells. It is difficult to identify the gonocyte in the seminiferous tubules in the...

Topics

Aging
Animals
Genes, Recessive
Growth Substances
Hypogonadism
Male
Mutation
Organ Size
Rats
Rats, Mutant Strains
Reference Values

Male hypogonadism as a candidate of deficiency of postnatal testicular growth or differentiating factor(s): a new autosomal recessive mutation in the rat.

Abstract excerpt

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