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Article

Professor Alfred Jost: The Builder of Modern Sex Differentiation

1 Jan 2008

Abstract excerpt

Professor Alfred Jost (1916-1991) is famous for his discovery of the Mullerian inhibitor, now called anti-Mullerian hormone (AMH) or Mullerian inhibiting substance (MIS). Alfred Jost resolved the controversy surrounding the mechanism of somatic sex differentiation by proving that male characteristics must be imposed on the fetus by the testicular hormones testosterone and AMH, respectively responsible for the...

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PMID: 18577872
DOI: 10.1159/000129690

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