Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ground glass and fibrotic change in children with surfactant protein C dysfunction mutations.

Pediatric pulmonology - 1 Jul 2021

DeBoer Emily M, Liptzin Deborah R, Humphries Stephen M, Lynch David A, Robison Kyle, Galambos Csaba, Dishop Megan K, Deterding Robin R, Weinman Jason P

Abstract excerpt

INTRODUCTION: Therapeutics exist to treat fibrotic lung disease in adults, but these have not been investigated in children. Defining biomarkers for pediatric fibrotic lung disease in children is crucial for clinical trials. Children with surfactant protein C (SFTPC) dysfunction mutations develop fibrotic lung disease over time. We evaluated chest computed tomography (CT) changes over time in children with SFTPC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Protein C

Share to Pulmonary Surfactant-Associated Protein C

Share to Surface-Active Agents

Source

Identifiers

PMID: 33666361
DOI: 10.1002/ppul.25356

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ground glass and fibrotic change in children with surfactant protein C dysfunction mutations.PMID 33666361Read ↗

Surfactant protein C gene (SFTPC) mutation-associated lung disease: high-resolution computed tomography (HRCT) findings and its relation to histological analysis.Semantic proximity Read ↗

Genetic disorders of surfactant protein dysfunction: when to consider and how to investigate.Semantic proximity Read ↗

Congenital surfactant protein B deficiency--emphasis on imaging.Semantic proximity Read ↗

Structural Lung Disease in Children and Adolescents With Severe Neurological Disorders.Semantic proximity Read ↗

Clinical, radiological and pathological features of ABCA3 mutations in children.Semantic proximity Read ↗

Characteristics of disorders associated with genetic mutations of surfactant protein C.Semantic proximity Read ↗

Chest computed tomography scans should be considered as a routine investigation in cystic fibrosis.Semantic proximity Read ↗

A disorder of surfactant metabolism without identified genetic mutations.Semantic proximity Read ↗

Inherited pulmonary surfactant metabolism disorders in Argentina: Differences between patients with SFTPC and ABCA3 variants.Semantic proximity Read ↗

Non-invasive management of infants with SFTPC pathogenic variantsSemantic proximity Read ↗

Comparison of Chest Ct Findings and Pulmonary Function Tests in Non-symptomatic Children with Rheumatic DiseasesSemantic proximity Read ↗

CT-abnormalities, bacteriology and symptoms of sinonasal disease in children with Cystic Fibrosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.