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TMEFF2 promoter hypermethylation is an unfavorable prognostic marker in gliomas

4 Mar 2021

Abstract excerpt

BACKGROUND: Transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2) is a transmembrane protein in the tomoregulin family. Little research has been performed to determine whether TMEFF2 methylation is a prognostic marker in adult diffuse gliomas. METHODS: In this study, we investigated TMEFF2 expression in surgical glioma tissue samples. In addition, we conducted bisulfite amplicon...

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PMID: 33663520
DOI: 10.1186/s12935-021-01818-x

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