Article
B2M overexpression correlates with malignancy and immune signatures in human gliomas.
Scientific reports - 3 Mar 2021
Zhang Hao, Cui Biqi, Zhou Yulai, Wang Xinxing, Wu Wantao, Wang Zeyu, Dai Ziyu, Cheng Quan, Yang Kui
Abstract excerpt
Because of the limited treatment strategy of gliomas, the key of diagnosis and treatment is finding new molecular biomarkers. Here, we explored the potential of β2-microglobulin (B2M) to serve as a hopeful candidate for immunotherapy or diagnostic biomarker in gliomas. The genomic profiles, clinical characteristics, and immune signatures were analyzed based on TCGA and CGGA databases. We carried out the whole...
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