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Article

Four childhood atopic dermatitis subtypes identified from trajectory and severity of disease and internally validated in a large UK birth cohort.

The British journal of dermatology - 1 Sept 2021

Mulick A R, Mansfield K E, Silverwood R J, Budu-Aggrey A, Roberts A, Custovic A, Pearce N, Irvine A D, Smeeth L, Abuabara K, Langan S M

Abstract excerpt

BACKGROUND: Atopic dermatitis (AD) disease activity and severity is highly variable during childhood. Early attempts to identify subtypes based on disease trajectory have assessed AD presence over time without incorporating severity. OBJECTIVES: To identify childhood AD subtypes from symptom severity and trajectories, and determine associations with genetic risk factors, comorbidities and demographic and...

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Identifiers

PMID: 33655501
DOI: 10.1111/bjd.19885
PMCID: PMC8410876

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