Article
TCF7L2 (rs7903146) But Not CDKAL1 (rs7754840) Gene Polymorphisms Increase the Risk of New-Onset Diabetes After Kidney Transplant.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation - 1 Nov 2023
Helvaci Özant, Korucu Berfu, Yeter Haci Hasan, Gönen Sevim, Cavnar Helvaci Burçak, Sanisoğlu Yavuz, Bali Musa, Güz Galip
Abstract excerpt
OBJECTIVES: Incidence of new-onset diabetes after transplant negatively affects graft and patient survival. Obesity, impaired fasting glucose before transplant, and a history of diabetes in first-degree relatives are well-defined risk factors. TCF7L2 and CDKAL1 gene polymorphisms have been implicated in the pathogenesis.We investigated the effect of single gene polymorphisms of TCF7L2 (rs7903146) and CDKAL1...
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