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Article

Sarcomere mutation negative hypertrophic cardiomyopathy is associated with ageing and obesity.

Open heart - 1 Feb 2021

de Feria Alejandro E, Kott Andrew E, Becker Jason R

Abstract excerpt

BACKGROUND: Despite advances in our understanding of the genetic causes of hypertrophic cardiomyopathy (HCM), a large portion of this patient population do not carry sarcomere gene mutations when screened. It remains largely unknown why patients without sarcomere mutations develop asymmetric myocardial hypertrophy. METHODS: We performed a retrospective analysis of probands with HCM who underwent genetic testing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33637569
DOI: 10.1136/openhrt-2020-001560
PMCID: PMC7919593

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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