Article
Sarcomere gene mutations in hypertrophy and heart failure.
Journal of cardiovascular translational research - 1 Aug 2010
Morita Hiroyuki, Nagai Ryozo, Seidman J G, Seidman Christine E
Abstract excerpt
Despite considerable progress in identifying and modifying risk factors that cause cardiovascular disease, heart failure has emerged as an important medical and socioeconomic problem. Hypertrophic remodeling, a common response to many cardiovascular disorders, increases the risk of heart failure. Discovery of the genetic basis of hypertrophic cardiomyopathy has allowed consideration of whether these genes also...
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