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Article

Exosome-mediated transfer of CD44 from high-metastatic ovarian cancer cells promotes migration and invasion of low-metastatic ovarian cancer cells.

Journal of ovarian research - 24 Feb 2021

Shen Xiameng, Wang Conghui, Zhu Huihui, Wang Yaping, Wang Xinyu, Cheng Xiaodong, Ge Wanzhong, Lu Weiguo

Abstract excerpt

OBJECTIVE: To investigate the detailed roles and mechanisms of tumor-derived exosomes in progression and metastasis of ovarian cancer in vitro. METHODS: Exosomes were isolated by differential centrifugation method; the morphology, size and biological markers of exosomes were separately defined by transmission electron microscopy, nanoS90 and Western blotting; Trans-well chambers assay was used to assess the...

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Identifiers

PMID: 33627162
DOI: 10.1186/s13048-021-00776-2
PMCID: PMC7905574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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