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Evolution, structure and emerging roles of C1ORF112 in DNA replication, DNA damage responses, and cancer

24 Feb 2021

Abstract excerpt

The C1ORF112 gene initially drew attention when it was found to be strongly co-expressed with several genes previously associated with cancer and implicated in DNA repair and cell cycle regulation, such as RAD51 and the BRCA genes. The molecular functions of C1ORF112 remain poorly understood, yet several studies have uncovered clues as to its potential functions. Here, we review the current knowledge on C1ORF112...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33625522
DOI: 10.1007/s00018-021-03789-8

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