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Biosynthetic Interrogation of Soil Metagenomes Reveals Metamarin, an Uncommon Cyclomarin Congener with Activity against Mycobacterium tuberculosis

23 Feb 2021

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High Resolution Image Download MS PowerPoint Slide Tuberculosis (TB) remains one of the deadliest infectious diseases. Unfortunately, the development of antibiotic resistance threatens our current therapeutic arsenal, which has necessitated the discovery and development of novel antibiotics against drug-resistant Mycobacterium tuberculosis ( Mtb ). Cyclomarin A and rufomycin I are structurally related cyclic...

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PMID: 33621083
DOI: 10.1021/acs.jnatprod.0c01104

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