Article
Severe Liver Injury Associated with Glecaprevir Plus Pibrentasvir Therapy in a Patient with Treatment-naïve Hepatitis C Virus Infection.
Internal medicine (Tokyo, Japan) - 1 Aug 2021
Hara Tasuku, Ohara Tomoya, Taniguchi Masashi, Sakai Hiroaki, Oka Kohei, Iwai Naoto, Tsuji Toshifumi, Okuda Takashi, Nagata Akihiro, Komaki Toshiyuki, Sakagami Junichi, Kagawa Keizo
Abstract excerpt
A 49-year-old man underwent treatment with glecaprevir plus pibrentasvir (G/P) for chronic hepatitis C infection. Six weeks later, he was admitted to our hospital because of jaundice and fatigue with no accompanying skin rash. A laboratory examination and evaluation of the patient's history resulted in a diagnosis of acute liver injury. Discontinuation of G/P and a rigorous medical protocol, including plasma...
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