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Decreased miR-149 expression in sperm is correlated with the quality of early embryonic development in conventional in vitro fertilization

18 Feb 2021

Abstract excerpt

miRNAs play a critical role in the regulation of highly orchestrated gene expression profiles during spermatogenesis and early human embryonic development. However, there is much less information available on the effects of sperm-borne miRNAs on human embryonic development than on spermatogenesis. This study was designed to assess the relationship between two sperm-borne miRNAs (miR-34c and miR-149) and...

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PMID: 33610732
DOI: 10.1016/j.reprotox.2021.02.005

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