Causal relationship between dietary macronutrient composition and anthropometric measures: A bidirectional two-sample Mendelian randomization analysis

Abstract excerpt

Background The question whether the proportion of energy provided by fat and carbohydrates in the diet is associated with body mass index (BMI) and waist circumference (WC) is an important public health issue, but determining causality is difficult in epidemiological studies. Objectives Using a two-sample bidirectional Mendelian randomization (MR) in both a univariable and multivariable setting, we aimed to...

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