Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sertoli cell‐derived exosomal MicroRNA‐486‐5p regulates differentiation of spermatogonial stem cell through PTEN in mice

19 Feb 2021

Abstract excerpt

Self-renewal and differentiation of spermatogonial stem cell (SSC) are critical for male fertility and reproduction, both of which are highly regulated by testicular microenvironment. Exosomal miRNAs have emerged as new components in intercellular communication. However, their roles in the differentiation of SSC remain unclear. Here, we observed miR-486-5p enriched in Sertoli cell and Sertoli cell-derived...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to MicroRNA in disease regulation
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33608983
DOI: 10.1111/jcmm.16347

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sertoli cell‐derived exosomal MicroRNA‐486‐5p regulates differentiation of spermatogonial stem cell through PTEN in micePMID 33608983Read ↗

Regulation of spermatogonial stem cell differentiation by Sertoli cells‐derived exosomes through paracrine and autocrine signalingSemantic proximity Read ↗

MicroRNA-322 Regulates Self-renewal of Mouse Spermatogonial Stem Cells through Rassf8Semantic proximity Read ↗

miRNA Signature in Mouse Spermatogonial Stem Cells Revealed by High-Throughput SequencingSemantic proximity Read ↗

Role of microRNAs in mammalian spermatogenesis and testicular germ cell tumorsSemantic proximity Read ↗

MicroRNA-30a-5p promotes differentiation in neonatal mouse spermatogonial stem cells (SSCs)Semantic proximity Read ↗

Sertoli cell‐derived exosome‐mediated transfer of miR‐145‐5p inhibits Leydig cell steroidogenesis by targeting steroidogenic factor 1Semantic proximity Read ↗

Roles of Spermatogonial Stem Cells in Spermatogenesis and Fertility RestorationSemantic proximity Read ↗

Spermatogonial stem cells, infertility and testicular cancerSemantic proximity Read ↗

Establishment of a proteome profile and identification of molecular markers for mouse spermatogonial stem cellsSemantic proximity Read ↗

Decoding the spermatogonial stem cell niche under physiological and recovery conditions in adult mice and humansSemantic proximity Read ↗

MicroRNA-21 regulates the self-renewal of mouse spermatogonial stem cellsSemantic proximity Read ↗

Signaling molecules and pathways regulating the fate of spermatogonial stem cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.