Differences between transient neonatal diabetes mellitus subtypes can guide diagnosis and therapy.

doi:10.1530/EJE-20-1030

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Article

Differences between transient neonatal diabetes mellitus subtypes can guide diagnosis and therapy.

European journal of endocrinology - 1 Apr 2021

Bonfanti Riccardo, Iafusco Dario, Rabbone Ivana, Diedenhofen Giacomo, Bizzarri Carla, Patera Patrizia Ippolita, Reinstadler Petra, Costantino Francesco, Calcaterra Valeria, Iughetti Lorenzo, Savastio Silvia, Favia Anna, Cardella Francesca, Lo Presti Donatella, Girtler Ylenia, Rabbiosi Sarah, D'Annunzio Giuseppe, Zanfardino Angela, Piscopo Alessia, Casaburo Francesca, Pintomalli Letizia, Russo Lucia, Grasso Valeria, Minuto Nicola, Mucciolo Mafalda, Novelli Antonio, Marucci Antonella, Piccini Barbara, Toni Sonia, Silvestri Francesca, Carrera Paola, Rigamonti Andrea, Frontino Giulio, Trada Michela, Tinti Davide, Delvecchio Maurizio, Rapini Novella, Schiaffini Riccardo, Mammì Corrado, Barbetti Fabrizio

Abstract excerpt

OBJECTIVE: Transient neonatal diabetes mellitus (TNDM) is caused by activating mutations in ABCC8 and KCNJ11 genes (KATP/TNDM) or by chromosome 6q24 abnormalities (6q24/TNDM). We wanted to assess whether these different genetic aetiologies result in distinct clinical features. DESIGN: Retrospective analysis of the Italian data set of patients with TNDM. METHODS: Clinical features and treatment of 22 KATP/TNDM...

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PMID: 33606663
DOI: 10.1530/EJE-20-1030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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