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Article

Mutations in ATP-sensitive K+ channel genes cause transient neonatal diabetes and permanent diabetes in childhood or adulthood.

Diabetes - 1 Jul 2007

Flanagan Sarah E, Patch Ann-Marie, Mackay Deborah J G, Edghill Emma L, Gloyn Anna L, Robinson David, Shield Julian P H, Temple Karen, Ellard Sian, Hattersley Andrew T

Abstract excerpt

Transient neonatal diabetes mellitus (TNDM) is diagnosed in the first 6 months of life, with remission in infancy or early childhood. For approximately 50% of patients, their diabetes will relapse in later life. The majority of cases result from anomalies of the imprinted region on chromosome 6q2...

Read the complete abstract on PubMed

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Share to Adenosine Triphosphate
Share to ATP-Binding Cassette Transporters

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus

Share to Infant, Newborn

Share to Potassium Channels

Share to Potassium Channels, Inwardly Rectifying

Share to Receptors, Drug

Share to Sulfonylurea Receptors

Source

Open in PubMed Open full text

Identifiers

PMID: 17446535
DOI: 10.2337/db07-0043
PMCID: PMC7611811

Genes

ABCC8
KCNJ11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17446535-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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