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Article

Clinical and Functional Characteristics of a Novel KLF11 Cys354Phe Variant Involved in Maturity-Onset Diabetes of the Young.

Journal of diabetes research - 1 Jan 2021

Sun Yujing, Qu Jingru, Wang Jing, Zhao Ruxing, Wang Chuan, Chen Li, Hou Xinguo

Abstract excerpt

BACKGROUND: Mutations in human KLF11 may lead to the development of maturity-onset diabetes of the young 7 (MODY7). This occurs due to impaired insulin synthesis in the pancreas. To date, the clinical and functional characteristics of the novel KLF11 mutation c.1061G > T have not yet been reported. METHODS: Whole-exon sequencing was used to screen the proband and family members with clinical suspicion of the...

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Identifiers

PMID: 33604390
DOI: 10.1155/2021/7136869
PMCID: PMC7870296

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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