Article
An organelle-tethering mechanism couples flagellation to cell division in bacteria.
Developmental cell - 8 Mar 2021
Siwach Manisha, Kumar Lokesh, Palani Saravanan, Muraleedharan Samada, Panis Gaël, Fumeaux Coralie, Mony Binny M, Sanyal Soumyajit, Viollier Patrick H, Radhakrishnan Sunish Kumar
Abstract excerpt
In some free-living and pathogenic bacteria, problems in the synthesis and assembly of early flagellar components can cause cell-division defects. However, the mechanism that couples cell division with the flagellar biogenesis has remained elusive. Herein, we discover the regulator MadA that controls transcription of flagellar and cell-division genes in Caulobacter crescentus. We demonstrate that MadA, a small...
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