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Isolation and characterization of two novel reassortant H5N6 avian influenza viruses from waterfowl in eastern China.

Archives of virology - 1 Apr 2021

Yang Fan, Xiao Yixin, Liu Fumin, Yao Hangping, Wu Nanping, Wu Haibo

Abstract excerpt

Waterfowl are considered to be the natural hosts of avian influenza virus. In 2017, two reassortant highly pathogenic H5N6 avian influenza viruses of clade 2.3.4.4, subclade II, were identified in wild birds in eastern China. Genome sequencing and phylogenetic and antigenicity analysis showed that the viruses originated from multiple reassortments. To evaluate their pathogenicity in mammals, 15 BALB/c mice were...

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PMID: 33598814
DOI: 10.1007/s00705-021-04995-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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