Article
Capmatinib for non-small cell lung cancer.
Drugs of today (Barcelona, Spain : 1998) - 1 Jan 2021
Alzofon N, Jimeno A
Abstract excerpt
Molecular profiling of non-small cell lung cancer (NSCLC) in the past decade has revealed numerous oncogenic driver events in NSCLC leading to several highly effective therapies. While a promising target, small-molecule inhibition of MET signaling has proven difficult. Capmatinib is a specific inhibitor of MET with Food and Drug Administration (FDA) accelerated approval in 2020 for the treatment of NSCLC...
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