Article
BipA exerts temperature-dependent translational control of biofilm-associated colony morphology in Vibrio cholerae.
eLife - 12 Feb 2021
Del Peso Santos Teresa, Alvarez Laura, Sit Brandon, Irazoki Oihane, Blake Jonathon, Warner Benjamin R, Warr Alyson R, Bala Anju, Benes Vladimir, Waldor Matthew K, Fredrick Kurt, Cava Felipe
Abstract excerpt
Adaptation to shifting temperatures is crucial for the survival of the bacterial pathogen Vibrio cholerae. Here, we show that colony rugosity, a biofilm-associated phenotype, is regulated by temperature in V. cholerae strains that naturally lack the master biofilm transcriptional regulator HapR. Using transposon-insertion mutagenesis, we found the V. cholerae ortholog of BipA, a conserved ribosome-associated...
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