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Identification of epigenetic memory candidates associated with gestational age at birth through analysis of methylome and transcriptional data

9 Feb 2021

Abstract excerpt

Preterm birth is known to be associated with chronic disease risk in adulthood whereby epigenetic memory may play a mechanistic role in disease susceptibility. Gestational age (GA) is the most important prognostic factor for preterm infants, and numerous DNA methylation alterations associated with GA have been revealed by epigenome-wide association studies. However, in human preterm infants, whether the...

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PMID: 33564054
DOI: 10.1038/s41598-021-83016-3

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