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Article

Epithelialized tunnels are a source of inflammation in hidradenitis suppurativa.

The Journal of allergy and clinical immunology - 1 Jun 2021

Navrazhina Kristina, Frew John W, Gilleaudeau Patricia, Sullivan-Whalen Mary, Garcet Sandra, Krueger James G

Abstract excerpt

BACKGROUND: Hidradenitis suppurativa (HS), also known as acne inversa, is a chronic, painful, and burdensome inflammatory disease manifesting in nodules and abscesses, with progression to chronically draining tunnels in later-stage disease. OBJECTIVE: We sought to determine whether HS tunnels are immunologically active participants in disease activity. METHODS: Skin biopsy specimens were obtained by using...

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Identifiers

PMID: 33548397
DOI: 10.1016/j.jaci.2020.12.651
PMCID: PMC8184580

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