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Article

Novel rare variants in FGFR1 and clinical characteristics analysis in a series of congenital hypogonadotropic hypogonadism patients.

Clinical endocrinology - 1 Jul 2021

Nie Min, Yu Bingqing, Chen Rongrong, Sun Bang, Mao Jiangfeng, Wang Xi, Zhang Hongbing, Wu Xueyan

Abstract excerpt

OBJECTIVE: We aimed to analyse FGFR1 rare variants in a series of Chinese congenital hypogonadotropic hypogonadism (CHH) patients. In addition, we intended to understand the clinical characteristics and the response to treatment of CHH patients with FGFR1 rare variants. PATIENTS AND METHODS: A total of 357 CHH patients were recruited at Peking Union Medical College Hospital. We used Sanger sequencing to analyse...

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PMID: 33548149
DOI: 10.1111/cen.14436

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