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Article

Atezolizumab prolongs overall survival over docetaxel in advanced non-small-cell lung cancer patients harboring STK11 or KEAP1 mutation.

Oncoimmunology - 15 Jan 2021

Nie Wei, Gan Lu, Wang Xin, Gu Kai, Qian Fang-Fei, Hu Min-Juan, Zhang Ding, Chen Shi-Qing, Lu Jun, Cao Shu-Hui, Li Jing-Wen, Wang Yue, Zhang Bo, Wang Shu-Yuan, Li Chang-Hui, Yang Ping, Xu Mi-Die, Zhang Xue-Yan, Zhong Hua, Han Bao-Hui

Abstract excerpt

Somatic mutations of STK11 or KEAP1 are associated with poor clinical outcomes for advanced non-small-cell lung cancer (aNSCLC) patients receiving immune checkpoint inhibitors (ICIs), chemotherapy, or targeted therapy. Which treatment regimens work better for STK11 or KEAP1 mutated (SKmut) aNSCLC patients is unknown. In this study, the efficacy of atezolizumab versus docetaxel in SKmut aNSCLC was compared. A...

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Identifiers

PMID: 33537171
DOI: 10.1080/2162402X.2020.1865670
PMCID: PMC7833760

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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