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Capsid opening enables genome release of iflaviruses

1 Jan 2021

Abstract excerpt

The family Iflaviridae includes economically important viruses of the western honeybee such as deformed wing virus, slow bee paralysis virus, and sacbrood virus. Iflaviruses have nonenveloped virions and capsids organized with icosahedral symmetry. The genome release of iflaviruses can be induced in vitro by exposure to acidic pH, implying that they enter cells by endocytosis. Genome release intermediates of...

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PMID: 33523856
DOI: 10.1126/sciadv.abd7130

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