Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

VIP modulates human macrophages phenotype via FPRL1 via activation of RhoA-GTPase and PLC pathways.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Mar 2021

Harhous Zeina, Faour Wissam H, El Zein Nabil

Abstract excerpt

OBJECTIVE AND DESIGN: This study is aimed at uncovering the signaling pathways activated by vasoactive intestinal peptide in human macrophages MATERIALS: Human peripheral blood mononuclear cell-derived macrophages were used for the in vitro investigation of the VIP-activated signaling pathways. METHODS AND TREATMENT: Time-course and dose-response experiments and siRNA were used in human macrophages co-challenged...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to p38 Mitogen-Activated Protein Kinases
Share to Extracellular Signal-Regulated MAP Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrogen Peroxide

Share to Matrix Metalloproteinase 9

Share to Proto-Oncogene Proteins c-akt

Share to rhoA GTP-Binding Protein

Share to Type C Phospholipases

Share to Vasoactive Intestinal Peptide

Source

Identifiers

PMID: 33502586
DOI: 10.1007/s00011-021-01436-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

VIP modulates human macrophages phenotype via FPRL1 via activation of RhoA-GTPase and PLC pathways.PMID 33502586Read ↗

Finding functional gaps: integrative analysis of VPAC1- and VPAC2-mediated signalling pathways in human lymphocytesSemantic proximity Read ↗

Vasoactive intestinal peptide maintains the nonpathogenic profile of human th17-polarized cells.Semantic proximity Read ↗

Recent advances in vasoactive intestinal peptide physiology and pathophysiology: focus on the gastrointestinal systemSemantic proximity Read ↗

PACAP and VIP Modulate LPS-Induced Microglial Activation and Trigger Distinct Phenotypic Changes in Murine BV2 Microglial Cells.Semantic proximity Read ↗

The Interferon Inducible Gene: ViperinSemantic proximity Read ↗

Analysis of the Expression and Clinical Significance of VIPR1 in Lung Adenocarcinoma Based on TCGA DatabaseSemantic proximity Read ↗

Viperin Differentially Induces Interferon-Stimulated Genes in Distinct Cell TypesSemantic proximity Read ↗

Rapid Recovery from COVID-19 Respiratory Failure with Comorbidity in 21 Patients Treated with Vasoactive Intestinal PeptideSemantic proximity Read ↗

Targeting VIP and PACAP Receptor Signalling: New Therapeutic Strategies in Multiple SclerosisSemantic proximity Read ↗

The Antiviral Cytomegalovirus Inducible Gene 5/Viperin Is Expressed in Atherosclerosis and Regulated by Proinflammatory AgentsSemantic proximity Read ↗

Identification of the early VIP-regulated transcriptome and its associated, interactome in resting and activated murine CD4 T cells.Semantic proximity Read ↗

Bone marrow-derived macrophages exclusively expressed caveolin-2: The role of inflammatory activators and hypoxia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.