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Possible host-adaptation of SARS-CoV-2 due to improved ACE2 receptor binding in mink

26 Nov 2020

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on mink farms are increasingly observed in several countries, leading to the massive culling of animals on affected farms. Recent studies showed multiple (anthropo)zoonotic transmission events between humans and mink on these farms. Mink-derived SARS-CoV-2 sequences from The Netherlands and Denmark contain multiple substitutions in the S...

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PMID: 33500787
DOI: 10.1093/ve/veaa094

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