Article
Oncogenic miRNA-1908 targets HDAC10 and promotes the aggressive phenotype of cervical cancer cell.
The Kaohsiung journal of medical sciences - 1 May 2021
Yu Dong-Sheng, Song Xiao-Lei, Yan Chao
Abstract excerpt
MicroRNAs (miRNAs) have vital functions in tumorigenesis and cancer progression. The significance of miR-1908 in cervical cancer has not been determined. We revealed that miR-1908 was notably upregulated in cervical cancer. Upregulation of miR-1908 increased cervical carcinoma cell growth and invasion. Downregulation of miR-1908 caused the opposite effects. We confirmed that histone deacetylase 10 (HDAC10) was a...
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