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Identification of 5‐Gene Signature Improves Lung Adenocarcinoma Prognostic Stratification Based on Differential Expression Invasion Genes of Molecular Subtypes

1 Jan 2020

Abstract excerpt

BACKGROUND: The acquisition of invasive tumor cell behavior is considered to be the cornerstone of the metastasis cascade. Thus, genetic markers associated with invasiveness can be stratified according to patient prognosis. In this study, we aimed to identify an invasive genetic trait and study its biological relevance in lung adenocarcinoma. METHODS: 250 TCGA patients with lung adenocarcinoma were used as the...

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PMID: 33490259
DOI: 10.1155/2020/8832739

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