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Article

Association of serum levels and receptor genes BsmI, TaqI and FokI polymorphisms of vitamin D with the severity of multiple sclerosis.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Feb 2021

Moosavi Ensieh, Rafiei Alireza, Yazdani Yaghoub, Eslami Mina, Saeedi Mohsen

Abstract excerpt

PURPOSE: Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease. Vitamin D has a major role in preventing inflammatory disorders. Therefore, any alteration in vitamin D receptor (VDR) might be a genetic risk factor for MS development. This study aimed to evaluate the effect of serum levels and VDR FokI, BsmI, and TaqI gene polymorphisms on the severity of MS. METHODS: This case-control...

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Case-Control Studies
Genetic Predisposition to Disease
Multiple Sclerosis
Polymorphism, Single Nucleotide
Receptors, Calcitriol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33485603
DOI: 10.1016/j.jocn.2020.12.008

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